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Polychlorinated Biphenyls (PCBs)
CAS ID #: 1336-36-3, 11097-69-1
Affected Organ Systems: Dermal (Skin), Developmental (effects during periods when organs are developing) , Endocrine (Glands and Hormones), Hepatic (Liver), Immunological (Immune System), Neurological (Nervous System)
Cancer Classification: EPA: Possibly carcinogenic to humans. IARC: Probably carcinogenic to humans. NTP: Known to be a human carcinogen
Please contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer classification.
Chemical Classification: Dioxins, Furans, PCBs (contain phenyl rings of carbon atoms), Pesticides (chemicals used for killing pests, such as rodents, insects, or plants)Summary: Polychlorinated biphenyls are mixtures of up to 209 individual chlorinated compounds (known as congeners). There are no known natural sources of PCBs. PCBs are either oily liquids or solids that are colorless to light yellow. Some PCBs can exist as a vapor in air. PCBs have no known smell or taste. Many commercial PCB mixtures are known in the U.S. by the trade name Aroclor.PCBs have been used as coolants and lubricants in transformers, capacitors, and other electrical equipment because they don't burn easily and are good insulators. The manufacture of PCBs was stopped in the U.S. in 1977 because of evidence they build up in the environment and can cause harmful health effects. Products made before 1977 that may contain PCBs include old fluorescent lighting fixtures and electrical devices containing PCB capacitors, and old microscope and hydraulic oils.
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Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile.
Provides an ongoing assessment of the exposure of the U.S. population to environmental chemicals using biomonitoring.
Toxicological and Health Professionals
Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance.
Addendum to the Toxicological Profile for Polychlorinated Biphenyls (PCBs) (April 2011)
Prioritization of substances based on a combination of their frequency, toxicity, and potential for human exposure at National Priorities List (NPL) sites.
The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure.
Succintly characterizes the toxicologic and adverse health effects information for mixtures of hazardous substances.
- Page last reviewed: March 3, 2011
- Page last updated: March 3, 2011
- Content source: Agency for Toxic Substances and Disease Registry
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