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Toxicological Profile for RDX

Title: Toxicological Profile for RDX

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): April 2010

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile was made available for a 90-day public comment period on July 30, 2010.

Peer Reviewers Provided with Public Comments before the Review: Yes

Anticipated Number of Reviewers: 3 or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Charge to Peer Reviewers: DTEM Charge to Peer Reviewers [PDF - 124 KB]

Peer Reviewers:

1. Gong, Ping


Academic and Professional Credentials

Ph.D., Ecotoxicology

Current Position Title

Senior Scientist

Organizational Affiliation(s)

SpecPro, Inc., Vicksburg, MS

Areas of Expertise, Discipline, Relevant Experiences

Dr. Gong has knowledge of RDX’s physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of risk to humans.

Recommended by Scientific/Professional Society or General Public

No

2. Kacew, Sam


Academic and Professional Credentials

B.Sc., M.Sc., Ph.D.

Current Position Title

Associate Director of Toxicology, McLaughlin Center for Population Health Risk Assessmsent

Organizational Affiliation(s)

University of Ottawa, Ottawa, Ontario

Areas of Expertise, Discipline, Relevant Experiences

Dr. Kacew has knowledge of RDX’s physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of risk to humans.

Recommended by Scientific/Professional Society or General Public

No

3. Meyer, Sharon A.


Academic and Professional Credentials

Ph.D.

Current Position Title

Associate Professor, Department of Toxicology, College of Health Sciences

Organizational Affiliation(s)

University of Louisiana at Monroe, Monroe, LA

Areas of Expertise, Discipline, Relevant Experiences

Dr. Meyer has knowledge of RDX’s physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of risk to humans.

Recommended by Scientific/Professional Society or General Public

No

Peer Reviewers’ Comments: RDX Summary Report [PDF - 2.26 MB]

CDC/ATSDR’s Response to Reviewers’ Comments: RDX Formal Disposition [PDF - 190 KB]

The ISI/HISA Dissemination Itself

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