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Toxicological Profile for Trichlorobenzenes

Title: Toxicological Profile for Trichlorobenzenes

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): August 2010

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile was made available for a 90-day public comment period on October 17, 2010.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3 or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Charge to Peer Reviewers: DTEM Charge to Peer Reviewers [PDF - 124 KB]

Peer Reviewers:

1. Kodell, Ralph L.


Academic and Professional Credentials

Ph.D.

Current Position Title

Professor, Biostatistics

Organizational Affiliation(s)

College of Public Health, University of Arkansas for Medical Sciences
American Statistical Association
Academy of Toxicological Sciences

Areas of Expertise, Discipline, Relevant Experiences

Dr. Kodell has knowledge of trichlorobenzenes’ physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of risk to humans.

Recommended by Scientific/Professional Society or General Public

No

2. Bull, Richard J.


Academic and Professional Credentials

Ph.D.

Current Position Title

President, MoBull Consulting, Richland Washington

Organizational Affiliation(s)

MoBull Consulting

Areas of Expertise, Discipline, Relevant Experiences

Dr. Bull has knowledge of trichlorobenzenes’ physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of risk to humans.

Recommended by Scientific/Professional Society or General Public

No

3. Klaunig, James E.


Academic and Professional Credentials

Ph.D.

Current Position Title

Professor and Chair, Department of Environmental Health, School of Public Health, Indiana University, Bloomington

Organizational Affiliation(s)

Indiana University
IU Simon Cancer Center

Areas of Expertise, Discipline, Relevant Experiences

Dr. Klaunig has knowledge of trichlorobenzenes’ physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of risk to humans.

Recommended by Scientific/Professional Society or General Public

No

Peer Reviewers’ Comments: Trichlorobenzene Summary Report [PDF - 10.9 MB]

CDC/ATSDR’s Response to Reviewers’ Comments: Trichlorobenzene Formal Disposition [PDF - 98 KB]

The ISI/HISA Dissemination Itself

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