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Toxicological Profile for Toluene Diisocyanate

Title: Toxicological Profile for Toluene Diisocyanate

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2014

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): ): A draft of this profile will be made available for public comment in 2015.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3 or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. Pemberton, Mark

Academic and Professional Credentials

PhD

Current Position Title

Principal Consultant

Organizational Affiliation(s)

Systox, Ltd.
84 Hazelwood Rd
Wilmslow, Cheshire, SK92QA
United Kingdom

Areas of Expertise, Discipline, Relevant Experiences

Mammalian and environmental toxicology expertise; regulatory compliance and conformity declarations, as well as the production of global product safety documentation. Chairman of the US Methacrylate Producers Association (MPA), Science Committee and the US Cyanide Council Toxicology Committee, the US Cyanide Counsel and a member of the US Acylonitrile Association; sits on several European, US and UK, National regulatory panels and workgroups; a member of the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) Scientific Committee

Recommended by Scientific/Professional Society or General Public

No

2. Prueiit, Robyn

Academic and Professional Credentials

PhD, DABT

Current Position Title

Senior Toxicologist

Organizational Affiliation(s)

Gradient Corporation
20 University Rd.
Cambridge, Massachusetts

Areas of Expertise, Discipline, Relevant Experiences

Toxicology, exposure assessment, cell and molecular biology, human genetics, environmental toxicology

Recommended by Scientific/Professional Society or General Public

No

3. Weeks, John A

Academic and Professional Credentials

PhD, DABT

Current Position Title

Research Associate

Organizational Affiliation(s)

Global Safety Assessment and Regulatory Affairs

S.C. Johnson & Son, Inc., Racine, WI

Areas of Expertise, Discipline, Relevant Experiences

Environmental assessment, environmental fate, ecotoxicology; Human and environmental safety assessment of consumer products, including laundry products, insect control products, cleaners, candles, industrial chemicals, radionuclides, insecticides, herbicides, and fungicides, etc.

Recommended by Scientific/Professional Society or General Public

No

Charge to Peer Reviewers: Charge to Peer Reviewers [PDF - 124 KB]

CDC/ATSDR’s Response to Reviewers’ Comments: Toluene Diisocyanate and Methylenediphenyl Diisocyanate Formal Disposition [PDF - 373 KB]

The ISI/HISA Dissemination Itself

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